How Does Cialis Work to treat Erectile Dysfunction and BPH?

Cialis is the trade name for tadalafil which is used in treating erectile dysfunction and benign prostatic hyperplasia (BPH). It belongs to a class of drugs known as phosphodiesterase type 5 inhibitors together with Viagra and levitra. All these drugs act to enhance erection in men who would otherwise be unable to achieve one and if they do, they find it difficult to retain it. With the help of cialis however, many men have been able to beat erectile dysfunction and are now able to achieve and maintain an erection for better sexual encounters and subsequently great relationships with spouses. To be noted however is that cialis does not increase sexual desire and one needs to be stimulated sexually for it to work. Those with physchological issues will not be helped by cialis in achieving an erection as the initial stimuli for it to start working is missing.

enlarged-prostateAs for its use in treating BPH which is characterized by a non-cancerous enlargement of the prostate gland, it works to alleviate the symptoms associated with it. Though the condition itself is not life-threatening, living with it is difficult. An enlarged prostate tends to press on the bladder and urethra making it difficult and at times painful to pass urine. Cialis counters these effects making it easier to pass urine.

How does cialis work in helping deal with these two conditions affecting men? Normally, when a man is sexually-aroused the nervous system in the penile tissue is stimulated to release a chemical known as nitric oxide. When this is released, a chemical messenger known as cyclic guanosine monophosphate (cGMP) is created in the smooth muscles of the blood vessels supplying the penile tissue. This has the effect of vasodilation in which it relaxes the smooth muscles causing increased blood flow to the penis. An increase in this blood flow results in achieving an erection. To stop this erection, an enzyme known as phosphodiesterase type 5 (pde5) is produced which acts to breakdown the cGMP easing its effects. This causes the blood vessels to contract reducing the amount of blood supplying the area causing the erection to cease. In people with erectile dysfunction, the action of the pde5 is exaggerated making it difficult for the men to achieve an erection. When such people take cialis however, it works to inhibit the action of this enzyme leading to the accumulation of cGMP which is not broken down. This causes an increase in the amount of blood flowing to the penile tissue causing an erection to be achieved and maintained. Note that without the initial production of nitric oxide when one is sexually stimulated, cialis would be useless.

In treating BPH, cialis works by a similar mechanism on the bladder muscles. It causes an accumulation of cGMP in the smooth muscles of the bladder making it relax and hence allow urine expulsion with ease. Cialis is also believed to increase the amount of blood supplied to the lower urinary tract organs especially the neck of the bladder resulting in dilation of the structures for easy urine expulsion. Though cialis will not help reduce the size of the prostate, its use will ensure that life for those suffering from the condition is much better.